99.8% Propitocaine Hydrochloride / Prilocaine HCl Antibacterial Drugs

Quick details 

Product NamePropitocaine hydrochloride
Aliasprilocainechloride; Prilocaine HCl
CAS1786-81-8
EINECS217-244-0
Purity99.0%
GradePharmaceutical Grade
M.F.C13H21ClN2O
M.W.256.77
AppearanceWhite crystalline powder
StorageOriginal package at cool dark place
ManufacturerPharmlab

Propitocaine HCl Description

Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.

In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia,which may be treated with methylene blue.


Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain) Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine,Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest),Bupivacaine (Marcaine), Etidocaine (Duranest).


Propitocaine hydrochloride Specification



Test
Analysis Standard
Results

Description
White Or Almost White Crystalline Powder
White Crystalline Powder

Melting Point
223-225ºC
223-224ºC

Loss On Drying
≤0.5%
0.22%

Residue On Ignition
≤0.1%
0.05%

Assay
≥98%
99.8%

Conclusion
Be Conform With Enterprise Standard



Propitocaine hydrochloride Application :

Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine).

The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into PARA-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest).

Related product lists for reference


Product name		CAS No.Product nameCAS No.
Benzocaine94-09-7Procaine59-46-1
Dapoxetine Hydrochloride129938-20-1Tetracaine HCl136-47-0
Clobetasol Propionate25122-46-7L-Thyroxine51-48-9
Finasteride98319-26-7Dydrogesterone152-62-5
Theophylline58-55-9/ 5967-84-0Valdecoxib181695-72-7
//Azithromycin117772-70-0/ 83905-01-5
Procaine HCl51-05-8Lidocaine HCl73-78-9
Lidocaine137-58-6 50-02-2
Dapoxetine119356-77-3L-Epinephrine hydrochloride55-31-2/ 329-63-5
Chloramphenicol56-75-7/ 2787-09-9Doxorubicin hydrochloride25316-40-9
Benzyl alcohol100-51-6Paclitaxel33069-62-4
Omeprazole73590-58-6/ 119141-89-8Benzyl benzoate120-51-4
Dutasteride164656-23-9Cyanocobalamin68-19-9/18195-32-9/ 13408-78-1
Benzocaine HCl23239-88-5Furazolidone67-45-8
Formestane566-48-3Rifaximin80621-81-4
Acetaminophen103-90-2Paromomycin7542-37-2
Amikacin disulfate salt39831-55-5/ 149022-22-0Nitazoxanide55981-09-4
Dexamethasone sodium phosphate55203-24-2/ 312-93-6Secnidazole

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