Selective Androgen Receptor Modulator Andarine S-4 AndarineGTX-007 for Muscle Wasting

S-4 (orarine) General information

Antioctic is an active part of the androgen receptor active agonist, S-4 is not only effective in maintaining lean body weight, but actually increases. Andarine is less potent in terms of anabolic and androgenic effects than other SARMs. In animal models of benign prostatic hypertrophy, the stamens are shown to reduce the weight of the prostate by similar effects of finasteride, but do not produce any reduction in muscle mass or antiandrogenic side effects. This suggests that it can competitively block the binding of dihydrotestosterone to the receptor target of the prostate, but its partial agonist action in the androgen receptor can prevent the association with the anti-androgenic drug that is traditionally used to treat BPH side effect.


How to use S4 safely

To counter any side effects, S-4 should be administered at a dose of 2 mg / kg at 5 days. If you are more than 50 milligrams, you will lose some night vision if your S4's quality is good. S-4 has a very short half-life of 2.6 hours, so it is perfect for use as a pulse, 3 times a week, before training should provide excellent strength and hardening effect. These two agreements will reduce the yellow eyes and night vision problems. Remember that PCT should be used after S4 (post-cycle treatment).
If you want the effect to be faster, the recommended cutting dose is 50mg for 6-8 weeks. Should be used every day, and then rest for 2 days. The length of the cycle per day of S-4 can lead to significant visual changes.


Product application

Andorra (GTX-007, S-4) is a research-selective androgen receptor modulator (SARM) developed by GTX for the treatment of diseases such as muscle wasting, osteoporosis and benign prostatic hypertrophy, The use of non-steroidal androgen antagonists bicalutamide as a lead compound.

Anlingling is an orally active part of the androgen receptor. Compared with other SARM, the effect of anabolic and androgen is lower. In animal models of benign prostatic hypertrophy, the stamens are shown to reduce the weight of the prostate by similar effects of finasteride, but do not produce any reduction in muscle mass or antiandrogenic side effects. This indicates that it is capable of competing to block dihydrotestosterone from its receptor targets in the prostate, but its role as a partial agonist in androgen receptors prevents side effects associated with antithrombin drugs that are traditionally used to treat BPH

S-4 belongs to a class of chemicals known as SARMS or selective androgen receptor modulators. Like typical androgen, SARMS binds to androgen receptors, but SARMS produces selective synthetic metabolic activity. Compared with testosterone and other anabolic steroids and hormones, the advantage of SARS, such as S-4, is that they do not have androgenic activity in muscle and muscle tissue in non-skeletal muscle.


Product effect

Lost body fat (cut)

Certain steroids are considered "cut" steroids, such as Winstrol and Anavar. These steroids do not provide much gain in muscle mass, but are very effective in tilting the body. SARM S-4 has a very similar nature, and S-4 exhibits binding affinity with AR, which indicates a similar fat burning effect. S-4 also shows a decrease in LPL (lipoprotein lipase), which is an enzyme that causes lipid accumulation.

S-4 is also suitable for cutting programs while reducing body fat while maintaining muscle mass in low temperature environments.
Because S4 has an anabolic and androgenic effect in muscle tissue, it not only helps to reduce fat, but also maintains or even increases muscle mass during cutting .S-4 leads to increased vascular distribution, promotes very good "quality" to the user's muscles, almost No or no water.

In this way, S-4 can be compared with Winstrol, without severe hair loss or extreme adverse effects on cholesterol.

There are other commonly used steroids / hormones for cutting, such as winstrol or epistane, which can significantly affect the dryness of the joints. S-4 did not suffer such consequences, so athletes are still able to lift weight to maintain / increase muscle mass and strength.

S-4 offers another advantage of cutting that it will not give painful pumps to other popular steroid / hormones. The back and calf pumps are particularly detrimental to cutting because it limits the ability to perform aerobic.

Strength gain and lean quality gains

Due to its androgenicity in muscle tissue, S-4 is a good agent with increased strength without swelling and weight gain. A dose of 50 mg + is the best point to achieve this benefit.

In addition, an increase in body weight as an oral steroid Anavar (Var) using S4 may not be as large as filling a steroid such as deca or Superdrol, but the lean body weight and strength obtained during the cycle remain unchanged after the cycle.

All dosing regimens were used because the half-life of S-4 was 4 hours, and it was suggested that the dose be divided into multiple applications.


Prodcut Usage

An experimental drug used to control lipids and increase HDL levels or high cholesterol
Blood flow.
As an effective, highly affluent PPARd agonist in cell infiltrated thiazolyl compounds. Show the selectivity of PPARd
Compared with PPARα and PPAR. No activity against other nuclear or non-nuclear receptors will occur.
It is reported that increased cholesterol efflux and ABAC1 expression in macrophages, fibroblasts and intestinal cells.


Advantage

In a study of catabolic status, 25 mg of healthy young men were given daily,
Short-term diet induces nitrogen waste.
After 7 days of this dose, the subject showed a continuous increase in serum concentration
In addition, the waste of nitrogen is reversed and has great potential for the treatment of diseases involving muscle wasting.
A study conducted to treat osteoporosis and bone mineral density showed an increase in bone mineral density, and therefore
The real impact on bone mineral density. This can help you recover your injuries during the cycle.



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