Local Anesthetic Drugs Procaine Hydrochloride Procaine HCl



Procaine HCl Specification

Product nameProcaine HCl
AppearanceWhite crystalline powder
Assay (C13H20N2O2¡¤HCl)99.0% to 101.0%99.5%
Melting point153~158ºC156.5~157.0ºC
Heavy metals≤20ppm<5ppm
Acidity≤0.02N NaOH 0.5ml0.3ml
Chromatographic puritySecondary spots≤0.5%,sum≤1.0%Conforms
Loss on drying≤1.0%0.06%
Residue on ignition≤0.15%0.03%
Bacterial endotoxins≤0.6EU/mg<0.6EU/mg


Procaine HCl description :

Procaine hydrochloride is a local anesthetic, can temporarily block the conduction of nerve fibers with anesthetic effect, strong role, low toxicity, and no addiction, but the skin, mucous membrane penetration is weak, not suitable for the surface Anesthesia, clinical mainly used for infiltration, spinal and conduction anesthesia.

White needle-like crystalline or crystalline powder at room temperature, odorless, taste slightly bitter and Ma, soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. Hydrochloric acid procaine structure in the ester bond can be hydrolyzed to generate amino acid and diethylamino ethanol, under certain conditions, p-aminobenzoic acid can be further decarboxylation to produce toxic aniline.

The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0 ~ 5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.

The product structure of aromatic primary amino group in dilute hydrochloric acid can generate diazonium salt with sodium nitrite, coupling reaction occurs when add alkaline β- naphthol, generating azo compounds scarlet.

Applications of procaine 

Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine LED to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.

Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase, which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

Related products:

Benzocaine base: / benzocaine /benzocaine/ procaine / lidocaine / lidocaie hcl / procaine hcl

Produt name:
Benzocaine Powder
Purity: 99.5%
CAS No.: 94-09-7
Appearance: White Crystal Powder
Usage: Local anesthetic.
Standard: USP/BP standard

Lidocaine base
Chemical Name: Lidocaine
Molecular Formula: C14H22N2O
Formula Weight: 234.34
CAS No.: 137-58-6
Pakcage: 25kg/drum
Usage: Local anesthetics

Peoduct name: Lidocaine hydrochloride
Cas: 73-78-9
MF: C14H23ClN2O
MW: 270.7982
Melting point: 350.8° C at 760 mmHg
Usage: Local anesthetics, antiarrhythmic drugs, used for a variety of anesthesia and rapid ventricular arrhythmia

Procaine
Product name: Procaine
CAS No.: 59-46-1
MF: C13H20N2O2
MW: 236.31
Purity: 99%
Appearance: White Crystalline Powder
Place of Origin: China
Standard: USP
Usage: Local anesthetics

 Procaine HCl Specification

Product nameProcaine HCl
AppearanceWhite crystalline powder
Assay (C13H20N2O2¡¤HCl)99.0% to 101.0%99.5%
Melting point153~158ºC156.5~157.0ºC
Heavy metals≤20ppm<5ppm
Acidity≤0.02N NaOH 0.5ml0.3ml
Chromatographic puritySecondary spots≤0.5%,sum≤1.0%Conforms
Loss on drying≤1.0%0.06%
Residue on ignition≤0.15%0.03%
Bacterial endotoxins≤0.6EU/mg<0.6EU/mg

Welcome to contact Miss Alsia
Skype:live:mxy04     
Email:marc@chembj.com
Whatsapp:+8615107134681
Mobilephone:+8615107134681
facebook:www.facebook.com/alisa.lee.58118
hit the below link , you will find more steroid products :

评论

发表评论

Anabolic Steroid Boldenone Cypionate dosage half-life effect

Bodybuilding Hormone Peptide Anabolic Steroids Weight Loss Tesamorelin 2mg/ Vial

图片
Tesamorelin  description Tesamorelin is a synthetic peptide consisting of all 44 amino acids of hGRF and a trans-3-hexenoic acid group is added. Trammolin (also known as Egrifta) is a synthetic form of growth hormone-releasing hormone for the treatment of HIV-associated lipodystrophy.  tendon fibroblasts in transwell filter migration assay revealed in a dose-dependent manner. BPC 157 also dose-dependent to accelerate the spread of tendon fibroblasts on petri dishes. F-actin formation was detected by FITC-phalloidin staining in fibroblasts treated with BPC 157. The protein expression and activation of FAK and puerarin were determined by Western blotting and the phosphorylation level of FAK and pudding protein was increased in a dose-dependent manner by BPC 157 while the total protein remained unchanged. In conclusion, BPC 157 promotes the in vitro growth of tendon fibroblasts from tendon explants, cell survival under stress, and in vitro migration of tendon fibroblasts, w
阅读全文

Polypeptide Hormones Epitalon for weight loss muscle

图片
Epitalon description Epithalon (also known as Epitalon or Epithalone) is a synthetic version of the human naturally occurring polypeptide Epithalamin. This pineal peptide preparation secreted in the epithlamium-epiphysealal region of the brain. Its prominent role is: to regulate the metabolism of bone regulation, increase the sensitivity of the hypothalamus to its natural hormones, the anterior pituitary function normalization, regulating the level of gonadotropin and melatonin in vivo. Epithalamin adds a person's resistance to emotional stress and is an antioxidant. Epitalon application Estroeil reduces the agerelated changes in immune and neuroendocrine systems and reduces the incidence of recurrent and chronic diseases. Long-term clinical trials have shown that epithalamin eliminates pre-oxidative and unbalanced antioxidant systems in age-related pathology patients. The 12-month treatment with Epithalon in patients with acc
阅读全文

Prohormone Powder Steroids Methylstenbolone Stenbolone for Gain Muscle Burning Fat

图片
What is Methylstenbolone? For beginners, Methylstenbolone is a hormone derived from dihydrotestosterone (DHT) that is formulated to increase strength, size and mass gain, so you can easily achieve your bodybuilding goals in the list. The chemical name is 2,17α-dimethyl-5α-androst-1-ene-17β-alcohol-3-one and is classified as anabolic steroid. This means that although methyl testosterone is completely different from most of its synthetic metabolic steroids in administration and administration, it will still be positive when you perform a steroid test. In addition to what is known as "methylbenzene", this hormone is also known by the user as "Msten" and "M-sten". In addition, Methylstenbolone is considered a safer, more convenient alternative to Superdrol. This is a quick action, the user can see the results in a few weeks. Interestingly, this compound has been recorded in the 4-week span of slimming muscle growth of up to 25 pounds. Now, alt
阅读全文